The column is inserted into the extracorporeal circuit through special adapters that allow it to be connected to the plasma separator plasma line or to the blood sampling line of the perfusion unit.

The column is built into the extracorporeal circuit through special connectors that allow it to be connected to the plasma line of the plasma separator or to the blood sampling line of the perfusion unit. During the extracorporeal procedure, the patient’s plasma (or blood) flows through the column. The target pathogenic molecules are specifically bound by a ligand. The purified blood is returned to the patient. The column is strictly specific to the target molecules, so there is no loss of protein during the procedure. The plasma flow rate through the column corresponds to the plasma flow, which is provided by venous access and the primary device for plasma production (plasma separator). The time of extracorporeal procedure is from 3 to 12 hours, depending on the type of procedure and pathology.

Hemosorption columns are disposable, and plasma adsorption columns are usually regenerable, and they can be used repeatedly for the same patient.